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Found 5 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50241089'
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50241089(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50241089(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50241089(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of Aurora B kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50241089(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Affinity DataIC50: <1nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50241089(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Affinity DataIC50:  15.5nMAssay Description:In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed