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Report error Found 10 Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor' and Ligand = 'BDBM25753'
TargetBeta-1 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataKi:  97.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H](-)-CGP12177 from human adrenergic beta1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataKi:  388nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 ADR expressed in HEK293T cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataIC50:  210nMAssay Description:Displacement of [3H](-)CGP12177 from human recombinant Beta-1 adrenergic receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataIC50:  210nMAssay Description:Displacement of [3H]CGP 12177 from human recombinant beta1 adrenergic receptor expressed in HEK293 cells measured after 60 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of human alpha1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataKd:  219nMpH: 7.4 T: 37°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM25753(2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl...)
Affinity DataKd:  24nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed