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Found 4 Enz. Inhib. hit(s) with Target = 'Beta-2 adrenergic receptor' and Ligand = 'BDBM50002134'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50002134(5-((2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl...)
Affinity DataKi:  7.92E+4nMAssay Description:Inhibition of I-iodocyanopindolol binding to human beta 2 adrenergic receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002134(5-((2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl...)
Affinity DataIC50:  9.77E+3nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002134(5-((2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl...)
Affinity DataIC50:  2.70E+5nMAssay Description:Compound was evaluated for its binding affinity towards Beta-2 adrenergic receptor in rat soleus membrane by displacing (-)-isoproterenol (50 microM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50002134(5-((2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl...)
Affinity DataEC50:  2.62E+5nMAssay Description:Agonistic activity was assessed by measurement of cAMP accumulation levels in CHO cells expressing human beta-2-adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed