Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50383839'
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant BACE1 using Glu-Ile-Asp-Leu-Met-Val-Leu-Asp as substrate incubated for 60 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP Swedish mutant assessed as reduction in amyloid beta 40 production after overnight incubatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50: 12nMAssay Description:Inhibition of BACE by cells based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50383839(CHEMBL2030997)
Affinity DataIC50: 13nMAssay Description:Inhibition of BACE in HEK293 cells by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed