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Report error Found 5 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50100518'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100518(CHEMBL3327064 | US10377744, Compound No. 2389)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100518(CHEMBL3327064 | US10377744, Compound No. 2389)
Affinity DataKi:  0.660nMAssay Description:FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100518(CHEMBL3327064 | US10377744, Compound No. 2389)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of rat soluble epoxide hydrolase using [3H]-t-DPPO as a substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California

US Patent
LigandPNGBDBM50100518(CHEMBL3327064 | US10377744, Compound No. 2389)
Affinity DataIC50:  5.5nMAssay Description:fluoresence competitive assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California

US Patent
LigandPNGBDBM50100518(CHEMBL3327064 | US10377744, Compound No. 2389)
Affinity DataIC50:  37.5nMAssay Description:Trans-diphenylpropene oxide is used in a radiometric competitive assay.More data for this Ligand-Target Pair
In DepthDetails US Patent