Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50185711'
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185711(CHEMBL3822935)
Affinity DataEC50:  150nMAssay Description:Agonist activity at GST-tagged FXR LBD (187 to 472 residues) (unknown origin) assessed as FXR interaction with b-CPSSHSSLTERHKILHRLLQEGSPS-COOH by FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185711(CHEMBL3822935)
Affinity DataEC50:  209nMAssay Description:Agonist activity at C-terminal Gal4-tagged human FXR (187 to 472 residues) expressed in HEK-293 cells co-expressing pFRluc by mammalian one hybrid as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed