Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50241116'
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241116BDBM50241116(CHEMBL4066332)
Affinity DataEC50:  20nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241116BDBM50241116(CHEMBL4066332)
Affinity DataEC50:  20nMAssay Description:Transactivation of human FXR expressed in human HeLa cells co-expressing BSEP after 24 hrs by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241116BDBM50241116(CHEMBL4066332)
Affinity DataEC50:  20nMAssay Description:Inhibition of FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241116BDBM50241116(CHEMBL4066332)
Affinity DataEC50:  20nMAssay Description:Agonist activity at recombinant human full-length FXR expressed in HeLa cells co-expressing human RXRalpha after 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241116BDBM50241116(CHEMBL4066332)
Affinity DataKd:  130nMAssay Description:Binding affinity to FXR ligand binding domain (unknown origin) isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed