Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50559586'
TargetBile acid receptor(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559586BDBM50559586(CHEMBL4756964)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human FXR-LBD transfected in human HEK293T cells co-expressing pFR-Luc/pRL assessed as reduction in GW4064-induced activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559586BDBM50559586(CHEMBL4756964)
Affinity DataKd:  300nMAssay Description:Binding affinity to recombinant FXR-LBD (unknown origin) expressed in Escherichia coli BL21 (DE3) gold cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed