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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Bile salt export pump' and Ligand = 'BDBM50103520'
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103520(2-(Trimethylammonio)Acetate | CHEBI:17750 | GLYCIN...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103520(2-(Trimethylammonio)Acetate | CHEBI:17750 | GLYCIN...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103520(2-(Trimethylammonio)Acetate | CHEBI:17750 | GLYCIN...)
Affinity DataIC50: >1.00E+6nMAssay Description:Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103520(2-(Trimethylammonio)Acetate | CHEBI:17750 | GLYCIN...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed