Found 14 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50563426' TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-CCR2-RA-(R) from human CCR2b expressed in human U2OS cell membranes pre-incubated for 4 hrs before radio ligand addition and mea...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]-CCR2-RA-(R) from human CCR2b expressed in human U2OS cell membranes pre-incubated for 4 hrs before radio ligand addition and mea...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-CCR2-RA-(R) from human CCR2b expressed in human U2OS cell membranes pre-incubated for 0 hrs before radio ligand addition and mea...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-CCR2-RA-(R) from human CCR2b expressed in human U2OS cell membranes pre-incubated for 0 hrs before radio ligand addition and mea...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-CCR2-RA from human CCR2b expressed in human U2OS cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-CCR2-RA from human CCR2b expressed in human U2OS cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 1.58nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from wild type human CCR2 expressed in CHO cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from wild type human CCR2 expressed in CHO cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CCR2 expressed in HEK293 cells assessed as inhibition of beta-arrestin recruitment pre-incubated for 20 mins before CCL2...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CCR2 expressed in HEK293 cells assessed as inhibition of beta-arrestin recruitment pre-incubated for 20 mins before CCL2...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human CCR2 expressed in HEK293 cells assessed as inhibition of beta-arrestin recruitment pre-incubated for 20 mins followed by...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human CCR2 expressed in HEK293 cells assessed as inhibition of beta-arrestin recruitment pre-incubated for 20 mins followed by...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human CCR2 expressed in human U2OS cell membranes as inhibition of [35S]GTPgammaS binding pre-incubated for 30 mins before CCL...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Leiden Academic Centre For Drug Research
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human CCR2 expressed in human U2OS cell membranes as inhibition of [35S]GTPgammaS binding pre-incubated for 30 mins before CCL...More data for this Ligand-Target Pair
