Found 7 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM50380881'
Affinity DataKi: 0.794nMAssay Description:Displacement of [125I]TARC from human CCR4 expressed in CHO membranes by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human CCR4 expressed in CHO membranes assessed as inhibition of [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human CCR4 expressed in CHO cell membranes by [35S]-GTPgammaS radioligand competition assayMore data for this Ligand-Target Pair
Affinity DataKd: 50.1nMAssay Description:Antagonist activity at human CCR4 in human whole blood assessed as inhibition of TARC-induced CD4+ CCR4+lymphocyte chemotaxis measuring F-actin conte...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Induction of CCR4 internalisation in human HUT78 cells after 30 mins by flow cytometryMore data for this Ligand-Target Pair