Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM50500893' TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-TARC from human recombinant CCR4 expressed in CHO cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at human CCR4 expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataEC50: 158nMAssay Description:Induction of CCR4 internalisation in human HUT78 cells after 30 mins by flow cytometryMore data for this Ligand-Target Pair
