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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM160935'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM160935(US10167299, Maraviroc | US9107954, maraviroc)
Affinity DataKi:  0.240nMAssay Description:Afterwards, the pharmacological profile of bivalent ligand 1 at the chemokine receptor CCR5 was characterized similarly. The competitive radioligand ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM160935(US10167299, Maraviroc | US9107954, maraviroc)
Affinity DataIC50:  2.20nMAssay Description:Then the Ca2+ functional activity of bivalent ligand 1 was evaluated in the Gqi5 transfected CCR5-MOLT-4 cells as described in the literature.3 As ex...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM160935(US10167299, Maraviroc | US9107954, maraviroc)
Affinity DataIC50:  7.38nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
In DepthDetails US Patent