Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor 1' and Ligand = 'BDBM50305735'
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(CHEMBL595990 | N,N'-(1,2-phenylene)bis(N-methyl-1-...)
Affinity DataIC50:  6.70nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(CHEMBL595990 | N,N'-(1,2-phenylene)bis(N-methyl-1-...)
Affinity DataIC50:  200nMAssay Description:Displacement of [125I]human anaphylatoxin C5a from human C5a receptor expressed in CHO cells co-expressed with Galpha16 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(CHEMBL595990 | N,N'-(1,2-phenylene)bis(N-methyl-1-...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(CHEMBL595990 | N,N'-(1,2-phenylene)bis(N-methyl-1-...)
Affinity DataIC50: >6.00E+4nMAssay Description:Antagonist activity at C5a receptor in rat RAW264.7 cells assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(CHEMBL595990 | N,N'-(1,2-phenylene)bis(N-methyl-1-...)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as effect on anaphylatoxin C5a-induced intracellula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed