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Found 8 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM21311'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataKi:  4.40nM EC50:  17.5nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataIC50:  0.770nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataEC50:  0.520nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at rat CB2 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed