Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM50395143'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50395143(CHEMBL2163578)
Show SMILES CC[C@H]1COc2cccc3c2n1cc(C(=O)NC1CCCCCC1)c3=O
Show InChI InChI=1S/C21H26N2O3/c1-2-15-13-26-18-11-7-10-16-19(18)23(15)12-17(20(16)24)21(25)22-14-8-5-3-4-6-9-14/h7,10-12,14-15H,2-6,8-9,13H2,1H3,(H,22,25)/t15-/m0/s1
Affinity DataKi:  9.24nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cell membranes incubated for 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50395143(CHEMBL2163578)
Show SMILES CC[C@H]1COc2cccc3c2n1cc(C(=O)NC1CCCCCC1)c3=O
Show InChI InChI=1S/C21H26N2O3/c1-2-15-13-26-18-11-7-10-16-19(18)23(15)12-17(20(16)24)21(25)22-14-8-5-3-4-6-9-14/h7,10-12,14-15H,2-6,8-9,13H2,1H3,(H,22,25)/t15-/m0/s1
Affinity DataKi:  11.4nMAssay Description:Displacement of [3H]CP-55940 from CB2 receptor in Sprague-Dawley rat spleen by scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50395143(CHEMBL2163578)
Show SMILES CC[C@H]1COc2cccc3c2n1cc(C(=O)NC1CCCCCC1)c3=O
Show InChI InChI=1S/C21H26N2O3/c1-2-15-13-26-18-11-7-10-16-19(18)23(15)12-17(20(16)24)21(25)22-14-8-5-3-4-6-9-14/h7,10-12,14-15H,2-6,8-9,13H2,1H3,(H,22,25)/t15-/m0/s1
Affinity DataKi:  187nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cell membranes incubated for 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50395143(CHEMBL2163578)
Show SMILES CC[C@H]1COc2cccc3c2n1cc(C(=O)NC1CCCCCC1)c3=O
Show InChI InChI=1S/C21H26N2O3/c1-2-15-13-26-18-11-7-10-16-19(18)23(15)12-17(20(16)24)21(25)22-14-8-5-3-4-6-9-14/h7,10-12,14-15H,2-6,8-9,13H2,1H3,(H,22,25)/t15-/m0/s1
Affinity DataKi:  203nMAssay Description:Displacement of [3H]CP-55940 from CB2 receptor in Sprague-Dawley rat spleen by scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50395143(CHEMBL2163578)
Show SMILES CC[C@H]1COc2cccc3c2n1cc(C(=O)NC1CCCCCC1)c3=O
Show InChI InChI=1S/C21H26N2O3/c1-2-15-13-26-18-11-7-10-16-19(18)23(15)12-17(20(16)24)21(25)22-14-8-5-3-4-6-9-14/h7,10-12,14-15H,2-6,8-9,13H2,1H3,(H,22,25)/t15-/m0/s1
Affinity DataIC50: 42nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50395143(CHEMBL2163578)
Show SMILES CC[C@H]1COc2cccc3c2n1cc(C(=O)NC1CCCCCC1)c3=O
Show InChI InChI=1S/C21H26N2O3/c1-2-15-13-26-18-11-7-10-16-19(18)23(15)12-17(20(16)24)21(25)22-14-8-5-3-4-6-9-14/h7,10-12,14-15H,2-6,8-9,13H2,1H3,(H,22,25)/t15-/m0/s1
Affinity DataIC50: 682nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair