Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM26979'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nM ΔG°:  -12.5kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nM ΔG°:  -12.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human carbonic anhydrase-1 by [18O]-exchange mass spectroscopyMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMpH: 8.3Assay Description:Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Show InChI InChI=1S/ClH/h1H/p-1
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair