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Found 13 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM26997'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  31.7nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nM ΔG°:  -8.41kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 measured by CO2 hydration reaction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMpH: 8.3Assay Description:Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition constant against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nM ΔG°:  -8.41kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM26997(CHEMBL364571 | PhAsO3H2 | benzenarsonic acid | ben...)
Affinity DataKi:  3.17E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed