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Report error Found 6 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM50429899'
TargetCarbonic anhydrase 1(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  0.110nMAssay Description:Inhibition of human carbonic anhydrase 1 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd: <10nMAssay Description:Inhibition of human carbonic anhydrase 1 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Horse)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  0.00320nMAssay Description:Binding affinity to CA1 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  0.110nMpH: 7.0Assay Description:Binding affinity to human recombinant CA1 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Rhesus macaque)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKon:  0.0000270M-1s-1Assay Description:Binding affinity to CA1 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd: <50nMAssay Description:Inhibition of human carbonic anhydrase 1 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed