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Report error Found 6 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 12' and Ligand = 'BDBM50031588'
TargetCarbonic anhydrase 12(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50031588(CHEMBL3359181)
Affinity DataKd:  3.30nMAssay Description:Inhibition of human carbonic anhydrase 12 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50031588(CHEMBL3359181)
Affinity DataKd:  6.70nMAssay Description:Inhibition of chimeric carbonic anhydrase 12 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 37 degC by fluorescent thermal sh...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50031588(CHEMBL3359181)
Affinity DataKd:  0.00450nMAssay Description:Binding affinity to CA12 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50031588(CHEMBL3359181)
Affinity DataKd: <10nMAssay Description:Inhibition of human carbonic anhydrase 12 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50031588(CHEMBL3359181)
Affinity DataKon:  0.000530M-1s-1Assay Description:Binding affinity to CA12 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50031588(CHEMBL3359181)
Affinity DataKd:  20nMAssay Description:Inhibition of human carbonic anhydrase 12 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair