Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 12' and Ligand = 'BDBM50163866'
TargetCarbonic anhydrase 12(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163866(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKoff:  1.80E+5s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163866(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKon:  0.0110M-1s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163866(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKd:  59nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163866(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKd:  17nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163866(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKon:  0.0110M-1s-1Assay Description:Binding affinity to CA12 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163866(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to CA12 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2019
Entry Details Article
PubMed