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Report error Found 8 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 9' and Ligand = 'BDBM50429899'
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  32nMAssay Description:Inhibition of human carbonic anhydrase 9 at pH7 and 37 degC by fluorescent thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  63nMAssay Description:Inhibition of chimeric carbonic anhydrase 9 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 37 degC by fluorescent thermal shi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  57nMAssay Description:Inhibition of human carbonic anhydrase 9 at pH7 and 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKon:  0.110M-1s-1Assay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  25nMAssay Description:Inhibition of human carbonic anhydrase 9 at pH7 and 25 degC by stopped-flow kinetic inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd: <5nMAssay Description:Inhibition of chimeric carbonic anhydrase 9 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 25 degC by stopped-flow kinetic in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  0.25nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic thermodynamic equilibrium constant at p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM50429899(CHEMBL2333416)
Affinity DataKd:  12nMAssay Description:Inhibition of chimeric carbonic anhydrase 9 (unknown origin) expressing with full length CA2 (1 to 260) at pH7 and 37 degC by isothermal titration ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed