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Found 5 Enz. Inhib. hit(s) with Target = 'Carnitine O-palmitoyltransferase 2, mitochondrial' and Ligand = 'BDBM50046145'
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50046145(2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4...)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of CPT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50046145(2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4...)
Affinity DataKi:  2.80E+3nMAssay Description:Competitive inhibition of CPT2 in heart mitochondria using carnitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50046145(2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4...)
Affinity DataKi:  4.20E+3nMAssay Description:Competitive inhibition of CPT2 in liver mitochondria using carnitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50046145(2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4...)
Affinity DataIC50:  4.75E+4nMAssay Description:Inhibition of rat CPT2 using [3H]carnitine by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50046145(2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4...)
Affinity DataIC50:  4.75E+4nMAssay Description:Inhibition of rat CPT2 using [3H]carnitine by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed