Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM10321'
TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10321((S)-1-Allyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]su...)
Affinity DataIC50: 4.60nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Glaxosmithkline

LigandPNGBDBM10321((S)-1-Allyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]su...)
Affinity DataIC50: 5nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed