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Found 1 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM19495'
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19495((2R)-N-(1-cyanocyclopropyl)-3-methanesulfonyl-2-{[...)
Affinity DataIC50:  10nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed