Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase' and Ligand = 'BDBM50582658'
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582658(CHEMBL4567157)
Affinity DataIC50:  110nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50582658(CHEMBL4567157)
Affinity DataIC50:  110nMAssay Description:Inhibition of cGAS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582658(CHEMBL4567157)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50582658(CHEMBL4567157)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of human cGASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50582658(CHEMBL4567157)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of human cGAS expressed in THP1-Dual cells transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed