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Found 2 Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase' and Ligand = 'BDBM50582680'
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582680(CHEMBL5076890)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582680(CHEMBL5076890)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cGAS expressed in THP1-Dual cells transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed