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Found 5 Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase' and Ligand = 'BDBM50582697'
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582697(CHEMBL5081956)
Affinity DataIC50:  27nMAssay Description:Inhibition of human cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582697(CHEMBL5081956)
Affinity DataIC50:  28nMAssay Description:Inhibition of human cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582697(CHEMBL5081956)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of cGAS in human THP-1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50582697(CHEMBL5081956)
Affinity DataIC50:  5.15E+3nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50582697(CHEMBL5081956)
Affinity DataIC50:  5.15E+3nMAssay Description:Inhibition of mouse cGASMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed