Found 8 Enz. Inhib. hit(s) with Target = 'Cyclin-A2/Cyclin-dependent kinase 2' and Ligand = 'BDBM2579'
Affinity DataKi: 2.90nM ΔG°: -48.2kJ/molepH: 7.4 T: 2°CAssay Description:In vitro CDK enzymatic assay using purified CDK mixed with cyclin A, was incubated with substrate, and test compounds in the presence of 1.4 uM ATP/ ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CDK2/cyclin-A using histone H1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.727nMAssay Description:Inhibition of human CDK2/cyclin-A using histone H1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) after 60 mins by Z-LYTE kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of full length human recombinant CDK2/Cyclin A using histone H1 as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiome...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged CDK2 (1 to 298 residues)/Cyclin A (174 to 432 residues) expressed in Escherichia coli Turner (DE3) cells as...More data for this Ligand-Target Pair