Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 12' and Ligand = 'BDBM50528813'
TargetCyclin-dependent kinase 12(Homo sapiens)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879)
Affinity DataIC50:  158nMAssay Description:Competitive irreversible inhibition of CDK12/cyclinK (unknown origin) in presence of Km ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879)
Affinity DataIC50:  158nMAssay Description:Inhibition of human CDK12/human cyclin K expressed in baculovirus-infected insect cells using pol2 CTD-peptide substrate and [gammaP]ATP by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879)
Affinity DataIC50:  483nMAssay Description:Inhibition of human recombinant CDK12/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed