Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Cysteinyl leukotriene receptor 1/2' and Ligand = 'BDBM50006812'
TargetCysteinyl leukotriene receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006812BDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of SRS-A-induced contractions in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006812BDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 50nMAssay Description:Inhibition of LTD4-induced contraction in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006812BDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 510nMAssay Description:Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006812BDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006812BDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataKd:  1.12E+3nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006812BDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed