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Found 2 Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM221978'
TargetCystic fibrosis transmembrane conductance regulator(Cricetulus griseus (Chinese hamster))
Novartis

US Patent
LigandPNGBDBM221978(US9303035, 4.1 | US9303035, 4.3)
Affinity DataIC50:  3.16nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Cricetulus griseus (Chinese hamster))
Novartis

US Patent
LigandPNGBDBM221978(US9303035, 4.1 | US9303035, 4.3)
Affinity DataIC50:  4.23nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent