Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM301439'
TargetCystic fibrosis transmembrane conductance regulator(Human)
Cystic Fibrosis Foundation Therapeutics

US Patent
LigandPNGBDBM301439(4-amino-7-{[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-...)
Affinity DataEC50:  27.1nMAssay Description:Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystic fibrosis transmembrane conductance regulator(Human)
Cystic Fibrosis Foundation Therapeutics

US Patent
LigandPNGBDBM301439(4-amino-7-{[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-...)
Affinity DataEC50:  23.3nMAssay Description:Fischer rat thyroid (FRT) cell lines stably expressing recombinant F508del V470 CFTR and halide-sensitive yellow fluorescent protein (Pedemonte et al...More data for this Ligand-Target Pair
In DepthDetails
US Patent