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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4/3A5' and Ligand = 'BDBM8610'
Target
Cytochrome P450 3A4/3A5
(Homo sapiens (Human))
Anhui Medical University
Curated by
ChEMBL
Ligand
BDBM8610
(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of CYP3A4/5 in human liver microsomes using Midazolam as substrate measured after 20 mins by LC-MS/MS analysis
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