Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Cytosolic phospholipase A2' and Ligand = 'BDBM50185348'
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185348(3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185348(3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human isolated cPLA2alpha by vescicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185348(3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...)
Affinity DataIC50:  5nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185348(3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185348(3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of cPLA2alpha activity assessed by A23187-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed