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Report error Found 7 Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM50004918'
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50004918(CHEMBL288090 | 3-Allyl-1-phenyl-2,3,4,5-tetrahydro...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as reversal of Ro 20-1724 mediated decrease in cAMP accumulation aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004918(CHEMBL288090 | 3-Allyl-1-phenyl-2,3,4,5-tetrahydro...)
Affinity DataKi:  10.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50004918(CHEMBL288090 | 3-Allyl-1-phenyl-2,3,4,5-tetrahydro...)
Affinity DataKi:  12nMAssay Description:The compound was evaluated for the dissociation constant for inhibiting the binding of [3H]-SCH- 23390 at Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004918(CHEMBL288090 | 3-Allyl-1-phenyl-2,3,4,5-tetrahydro...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004918(CHEMBL288090 | 3-Allyl-1-phenyl-2,3,4,5-tetrahydro...)
Affinity DataEC50:  25nMAssay Description:Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50004918(CHEMBL288090 | 3-Allyl-1-phenyl-2,3,4,5-tetrahydro...)
Affinity DataKi:  73nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50004918(CHEMBL288090 | 3-Allyl-1-phenyl-2,3,4,5-tetrahydro...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as assessed as increase in beta-arrestin-2 recruitment after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed