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Found 3 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM185687'
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM185687(UNC10107968 | US9156822, 17)
Affinity DataKi:  1.29nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM185687(UNC10107968 | US9156822, 17)
Affinity DataEC50:  4.60nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM185687(UNC10107968 | US9156822, 17)
Affinity DataEC50:  0.200nMpH: 7.4Assay Description:HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...More data for this Ligand-Target Pair
In DepthDetails US Patent