Affinity DataKi: 64nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Compound was evaluated for the binding affinity at Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPIMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 285nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 303nMAssay Description:Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:It is well-known that drug compounds that have an affinity for the striatal dopamine D2 may give rise to adverse side effects, such as short-term ext...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:The functional antagonist assay was performed as described in Payne, S. L et al. (2002) J. Neurochem., 82: 1106-1117, hereby incorporated by referenc...More data for this Ligand-Target Pair
Affinity DataIC50: 444nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H]spiperone to Dopamine receptor D2 in rat brain synaptic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 565nMAssay Description:In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against dopamine receptor D2 by 3H ligand binding experiments.More data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptorMore data for this Ligand-Target Pair