Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50010289'
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  5.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  10nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  12nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H] spiperone from human D2 dopamine receptor expressed in monkey caudate-putamen membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  13nMAssay Description:Binding affinity against dopamine receptor D2 by using [3H]spiperone as radioligand in caudate-putamen of monkeyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  19nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  20nMAssay Description:Affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  34nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010289BDBM50010289((S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  90nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed