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Report error Found 15 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50017543'
TargetD(2) dopamine receptor(Human)
Tianjin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKi:  1nMAssay Description:Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against Dopamine receptor D2 in rat corpus striatum using [3H]Apomorphine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Tianjin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKi:  4nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]U-86170.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKd:  4nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Tianjin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKi:  4nMAssay Description:Binding affinity to D2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Human)
Tianjin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKi:  26nMAssay Description:Displacement of [125]iodosulpride from human recombinant dopamine D2L receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKd:  30nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKd:  40nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKd:  45nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf corpus striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Tianjin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017543BDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKi:  50nMAssay Description:Affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed