Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50019949'
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKd:  8.5nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKd:  8.5nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataIC50: 47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKi:  7.60nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019949(CHEMBL54206 | 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-p...)
Affinity DataKi:  7.60nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed