Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50054067'
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  0.5nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  5nMAssay Description:In vitro ability to displace [3H]pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  34nMAssay Description:In vitro binding affinity at human Dopamine receptor D2 expressed in CHO K1 cells was measured by its ability to displace [3H]- N-0437More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  34nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]spiperone from human D2S receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  56nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKd:  300nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKi:  340nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKd:  400nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKd:  1.00E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Texas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054067BDBM50054067((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-...)
Affinity DataKd:  1.10E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S193A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed