Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50241119'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]raclopride from human D2 dopamine receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]YM-09151-2 from rat striatum D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  2.20nMAssay Description:Agonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]nemonapride from dopamine D2L receptor (unknown origin) expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataKi:  8.81nM ΔG°:  -46.0kJ/molepH: 7.4 T: 2°CAssay Description:Human-cloned dopamine D2L receptors stably expressed in C6 rat glioma cells (kindly donated by Professor Roberto Maggio, Università di L'Aquil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzoo...)
Affinity DataIC50:  2.90nMAssay Description:Antagonist activity at human D2 dopamine receptor expressed in CHO cell membrane by GTPgammaS-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed