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Report error Found 3 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A/B' and Ligand = 'BDBM50393079'
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  9nMpH: 7.6Assay Description:The ATP hydrolysis activity of S. aureus DNA gyrase is measured by coupling the production of ADP through pyruvate kinase/lactate dehydrogenase to th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using pBR322 plasmid DNA as substrate by coupled enzyme reaction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi: <21nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed