Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50242374'
TargetDNA topoisomerase 1(Green monkey)
Kumamoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242374BDBM50242374(topostatin | CHEMBL505529)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition topoisomerase 1 in african green monkey Vero cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242374BDBM50242374(topostatin | CHEMBL505529)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition topoisomerase 1 in human HeLa cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Mouse)
Kumamoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242374BDBM50242374(topostatin | CHEMBL505529)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition topoisomerase 1 in mouse NIH/3T3 cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242374BDBM50242374(topostatin | CHEMBL505529)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition topoisomerase 1 in human COLO201 cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242374BDBM50242374(topostatin | CHEMBL505529)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition topoisomerase 1 in human A549 cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed