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Found 3 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM321155'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321155(US10174049, Example 22 | US10385066, Example 22 | ...)
Affinity DataIC50:  1.80nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321155(US10174049, Example 22 | US10385066, Example 22 | ...)
Affinity DataIC50:  1.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321155(US10174049, Example 22 | US10385066, Example 22 | ...)
Affinity DataIC50:  1.80nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
In DepthDetails US Patent