Found 3 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50151246' TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
San Raffaele Scientific Institute
Curated by ChEMBL
San Raffaele Scientific Institute
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
San Raffaele Scientific Institute
Curated by ChEMBL
San Raffaele Scientific Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ADAM-17 in human KM-H2 cells assessed as reduction in pervanadate-induced soluble ALCAM shedding after 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
San Raffaele Scientific Institute
Curated by ChEMBL
San Raffaele Scientific Institute
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of ADAM-17 in human L428 cells assessed as reduction in pervanadate-induced soluble ALCAM shedding after 24 hrs by ELISAMore data for this Ligand-Target Pair
