BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-18,20-1210,C797S]' and Ligand = 'BDBM112499'

Epidermal growth factor receptor [1-18,20-1210,C797S](Homo sapiens (Human))
Boehringer Ingelheim International

WIPO

BDBM112499(DACOMITINIB | US8623883, No. 2 | WO2022090481, Exa...)

IC50: 1.60nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair

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3D Structure (crystal)