Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E' and Ligand = 'BDBM50543775'
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50543775(CHEMBL4640985)
Affinity DataKd:  18nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50543775(CHEMBL4640985)
Affinity DataKd:  17.7nMAssay Description:Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Rabbit)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50543775(CHEMBL4640985)
Affinity DataIC50: 280nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Rabbit)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50543775(CHEMBL4640985)
Affinity DataIC50: 280nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte lysate system assessed as reduction in ARCA mRNA cap-dependent translation measured after 60 mins by lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed