Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E-binding protein 1' and Ligand = 'BDBM545217'
TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
eFFECTOR Therapeutics, Inc.

US Patent
LigandPNGBDBM545217(US11286268, Compound 703)
Show SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(C)(CO)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1
Show InChI InChI=1S/C32H27Cl2N5O5S/c1-16-8-20(29-27(36-16)22(12-45-29)31(42)43)19-9-18(33)4-5-25(19)44-7-6-39-17(2)37-24-10-23(34)28(21(11-35)26(24)30(39)41)38-13-32(3,14-38)15-40/h4-5,8-10,12,40H,6-7,13-15H2,1-3H3,(H,42,43)
Affinity DataIC50: 3.18nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid